JTS CPG Development Process

JTS: tools for implementing domain-specific languages

The Jakarta Tool Suite (JTS) aims to reduce substantially the cost of generator development by providing domainindependent tools for creating domain-specific languages and component-based generators called GenVoca generators. JTS is a set of precompiler-compiler tools for extending industrial programming languages (e.g., Java) with domain-specific constructs. JTS is itself a GenVoca generator, ...

CpG - Binding Impaired Memory CD 8 T Cell Development

CpG and Non-CpG Oligodeoxynucleotides

Process Development: Maximizing Process Data from Development to Manufacturing

Process development and manufacturing for biopharmaceuticals are often disjointed activities. Disconnects among groups are aggravated by a lack of common terminology and poor data management practices. A UK biotech consortium has initiated a collaborative development effort to address data management issues. The proposed outcome is a data model, based on the ISA-88 Standard for Batch Control, t...

CpG binding protein is crucial for early embryonic development.

Epigenetic modification of DNA via CpG methylation is essential for the proper regulation of gene expression during embryonic development. Methylation of CpG motifs results in gene repression, while CpG island-containing genes are maintained in an unmethylated state and are transcriptionally active. The molecular mechanisms involved in maintaining the hypomethylation of CpG islands remain uncle...